Case Study

Increasing Patient Recruitment for Rare Neurological Disease Phase-2 Clinical Trials


patients engaged


increase in screening visits


interested visitors

Client Situation

A pharmaceutical company focusing on a rare neurological disease had been recruiting for phase-2 clinical trials for more than a year. During this year, they noticed a significant decrease in patient recruitment in their study.


Their initial approach was to use their patient lists of the study sites. However, their patient lists had been exhausted, and incremental recruitment was proving difficult, expensive, and slow. To improve ongoing efforts, PAS created digital recruitment campaigns. Based on previously !RB-approved language, our approach designed digital outreach materials which ensured timely approval from patients. Herein, we designed two study web pages – (i) for patients and (ii) for caregivers were launched. These web pages featur•ed embedded digital contact capture that allowed for interested visitors to efficiently leave their details. Furthermore, digital marketing efforts were launched on multiple channels, targeting Amyotrophic Lateral Sclerosis (ALS) demographics most key to the study.


The launch of the online campaign showed an increase in recruitment and retention of patients involved in clinical trials. PAS was able to accelerate patient enrollment through analysis of patient involvement from our designed digital outreach materials. Within 3 months of utilizing our digital services, the online campaign drove the following: • 600,000 interested visitors • 18,000 patients engaged • 140 patients referred to the study • 75% increase in screening visits

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