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Case Study

Increasing Patient Recruitment for Rare Neurological Disease Phase-2 Clinical Trials

18,000

Patients Engaged Through Targeted Digital Outreach

75%

Increase In Screening Visits

600k

Interested Visitors Reached Through the Campaign

Client Situation

A pharmaceutical sponsor conducting a Phase 2 clinical trial for a rare neurological disease was experiencing a significant decline in patient recruitment after more than a year of active enrollment efforts.

With site-based patient lists largely exhausted, the sponsor needed a more scalable way to reach, educate, and engage eligible patients and caregivers while maintaining a compliant, study-appropriate recruitment approach.

Approach

PAS developed and launched a targeted digital recruitment strategy designed to expand awareness beyond traditional site lists and create a more efficient pathway from patient interest to study referral.

Using previously IRB-approved language as the foundation, PAS created patient- and caregiver-facing digital outreach materials that could move through review efficiently while remaining aligned with study requirements. The campaign included two dedicated study webpages — one for patients and one for caregivers — each built with embedded contact-capture functionality to help interested visitors easily raise their hands and take the next step.

To drive qualified engagement, PAS also activated digital marketing efforts across multiple channels, targeting the patient and caregiver demographics most relevant to the study. This approach helped the sponsor move beyond exhausted recruitment lists and create a broader, more responsive recruitment funnel.

Result

Within three months of launch, the PAS-led digital recruitment campaign increased patient engagement, generated meaningful study interest, and helped drive more qualified patients toward screening.

The campaign reached 600,000 interested visitors, engaged 18,000 patients, referred 140 patients to the study, and contributed to a 75% increase in screening visits.

By combining compliant digital outreach, patient- and caregiver-specific education, and a streamlined contact-capture pathway, PAS helped the sponsor accelerate recruitment momentum for a rare disease trial that had previously become difficult, expensive, and slow to enroll.

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