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Case Study

Gene Therapy Trial Awareness Through Patient Engagement

30%

Increase In Patient Interest

6 Months

Ahead of Projected Timeline

Significant Growth

In Study Evaluations and Enrollment

Client Situation

A clinical-stage gene therapy company developing a potential treatment for a neurological condition sought to increase awareness of its clinical trial among patients, caregivers, and healthcare professionals. While the study represented a promising investigational approach, the sponsor identified gaps in patient education and trial awareness that limited engagement with potential participants.

The company needed a strategy that could educate key stakeholders, improve understanding of the study opportunity, and help connect qualified patients with clinical trial sites and screening resources.

Approach

PAS partnered with the sponsor and key cross-functional stakeholders to better understand the patient journey and identify barriers that could prevent participation in the clinical trial. Through discussions with patients, caregivers, healthcare providers, investigators, and primary care physicians, PAS gathered insights into critical informational needs and gaps affecting awareness and enrollment decisions.

Using these insights, PAS developed an integrated patient engagement and awareness strategy designed to educate, inform, and activate potential participants. The initiative included collaboration with patient advocacy organizations, educational programming, in-person and virtual engagement activities, key opinion leader (KOL) events, patient-focused support initiatives, and the launch of a dedicated study website. These efforts provided patients and families with accessible information about the clinical trial and created multiple pathways for engagement.

By leveraging trusted advocacy relationships and targeted educational outreach, PAS helped expand awareness of the study while supporting informed decision-making among potential participants and their care teams.

Result

The patient engagement and awareness campaign successfully increased visibility of the clinical trial and generated meaningful interest among prospective participants. The initiative contributed to a 30% increase in patient interest while accelerating study progress by six months compared to projected timelines. The sponsor also experienced significant growth in study evaluations and enrollment activity.

Through a coordinated strategy that combined patient education, advocacy engagement, healthcare provider outreach, and digital awareness initiatives, PAS helped the sponsor build a stronger connection with the patient community, improve awareness of the trial opportunity, and support faster enrollment progress.

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